Abstract
DNA, the operating element of the genes, brings the coded notes of inheritance in every single surviving thing: animals, plants, bacteria, and other microorganisms. Within human beings, the information-bringing DNA arises in each cell having nucleus, including cells surrounding hair roots, spermatozoa, white blood corpuscles, and salivary cells. These would be the cells of utmost significance in forensic investigations. DNA testing has countless prospective advantages for civil and criminal justice; in spite of this, because of the likelihood for its mishandling or abuse, vital issues have been mentioned about trustworthiness, authenticity, and privacy. The methods of DNA testing are results of the innovation in molecular biology that is generating an increase of knowledge about human genetics. The greatly personal and complex info that can be developed by DNA testing involves firm and meticulous knowledge of genetic basis of testing methods.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Botstein D, White RL, Skolnick M, Davis RW (1980) Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet 32:314–331
Butler J (2005) Forensic DNA typing: biology, technology, and genetics of STR markers. 2nd ed. Academic Press, Amsterdam, p 688, ISBN: 9780080470610
Committee on DNA Technology in Forensic Science, National Research Council (1997) DNA Technology in Forensic Science. National Academy of Sciences, Washington, DC
Cooper DN, Smith BA, Cooke HJ, Niemann S, Schmidtke J (1985) An estimate of unique DNA sequence heterozygosity in the human genome. Hum Genet 69:201–205
Fan H, Chu JY (2007) A brief review of short tandem repeat mutation. Genomics Proteomics Bioinformatics 5:7–14
Farley MA, Harrington JJ (1991) Forensic DNA technology. Lewis Publishers, Chelsea
Geserick G, Wirth I (2012) Genetic kinship investigation from blood groups to DNA markers. Transfus Med Hemother 39:163–175
Gill P, Jeffreys AJ, Werrett DJ (1985) Forensic application of DNA “fingerprints”. Nature 318:577–579
Helminen P, Ehnholm C, Lokki ML, Jeffreys A, Peltonen L (1988) Application of DNA “fingerprints” to paternity determinations. Lancet 1:574–576
Jeffreys AJ, Wilson V, Thein SL (1985) Individual-specific “fingerprints” of human DNA. Nature 316:75–79
Jeffreys AJ, Wilson V, Thein SL, Weatherall DJ, Ponder BAJ (1986) DNA “fingerprints” and segregation analysis of multiple markers in human pedigrees. Am J Hum Genet 39:11–24
Karkanaki A, Praras N, Katsikis I, Kita M, Panidis D (2007) Is the Y chromosome all that is required for sex determination? Hippokratia 11:120–123
Kirby LT (1990) DNA fingerprinting: an introduction. Stockton Press, New York
Lively TN, Jurema MW, Shields GC (1994) Hydrogen bonding of nucleotide base pairs: application of the PM3 method. Int J Quantum Chem 52:95–105
Nishitani H, Lygerou Z (2002) Control of DNA replication licensing in a cell cycle. Genes Cells 7:523–534
Orgogozo V, Morizot B, Martin A (2015) The differential view of genotype–phenotype relationships. Front Genet 6:179
Patrushev LI, Kovalenko TF (2014) Functions of noncoding sequences in mammalian genomes. Biochemistry 79:1442–1469
Roychoudhury AK, Nei M (1988) Human polymorphism genes: world distribution. Oxford University Press, New York
Southern EM (1975) Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 98:503–527
U.S. Department of Justice, Federal Bureau of Investigation (1991) Proceedings of the international symposium on the forensic aspects of DNA analysis. U.S. Government Printing Office, Washington, DC
White PS, Sulman EP, Porter CJ, Matise TC (1999) A comprehensive view of human chromosome 1. Genome Res 9:978–988
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Sinha, M., Arjun Rao, I., Mitra, M. (2018). Molecular Basis of Identification Through DNA Fingerprinting in Humans. In: Dash, H., Shrivastava, P., Mohapatra, B., Das, S. (eds) DNA Fingerprinting: Advancements and Future Endeavors. Springer, Singapore. https://doi.org/10.1007/978-981-13-1583-1_7
Download citation
DOI: https://doi.org/10.1007/978-981-13-1583-1_7
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-13-1582-4
Online ISBN: 978-981-13-1583-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)